Chapters
Status | Drug name | NICE TAs | Comments |
---|---|---|---|
Acenocoumarol tablets | |||
Apixaban | Specialist initiation for the treatment and secondary prevention of DVT and/or PE - use in line with NICE and supported by RICaD | ||
Apixaban | Second choice following diagnosis of AF - use in line with NICE | ||
Apixaban | Use following hip and knee surgery - full course of treatment supplied on discharge | ||
Argatronban | |||
Bivalirudin 250mg injection | Hospital use only | ||
Dabigatran capsules | Following diagnosis of AF – use in line NICE and toolkit, initiation/recommendation by haematologist, transfer to GP with RICaD. For the treatment and secondary prevention of DVT and/or PE - use in line with NICE. Initiation/recommendation by haematologist, transfer to GP with RICaD Adults only | ||
Dabigatran capsules | Use following hip and knee surgery – full course of treatment supplied on discharge | ||
Danaparoid injection | Hospital use only | ||
Edoxaban | First choice following a diagnosis of AF - use in line with NICE | ||
Edoxaban | Specialist initiation - For the treatment and secondary prevention of DVT and/or PE - use in line with NICE and supported by RICaD | ||
Enoxaparin Injection | For all other indications. The APC's view is that on clinical grounds, the status for certain indications approved by APC should be amber, supported by an ESCA. However, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain red (ESCAs to be developed). | ||
Epoprostenol injection | Hospital use only | ||
Fondaparinux injection | Hospital use only | ||
Heparin sodium injection | Hospital use only | ||
Idarucizumab 2.5g/250ml solution for injection/infusion | When rapid reversal of Dabigatran anticoagulant effect is required | ||
Phenindione tablets | |||
Protamine sulphate injection | Hospital use only | ||
Rivaroxaban tablets |
|
| |
Rivaroxaban tablets | BSSE APC preferred agent. This recommendation must only be taken into account after a patient and prescriber have discussed all treatment options (including warfarin) and only if they have no preference about which medicine they want to use. | ||
Taurolock | Hospital use only | ||
Taurolock Hep 500 | Hospital use only | ||
Warfarin tablets | First choice. BSSE APC preferred agent. This recommendation must only be taken into account after a patient and prescriber have discussed all treatment options (including warfarin) and only if they have no preference about which medicine they want to use. To be initiated by those who have the appropriate skills and experience. Use should be in line with local commissioning arrangements - for BCC CCG - Anticoagulation AQP. Ensure that patients prescribed anticoagulants receive appropriate verbal and written information at the start of therapy, at hospital discharge, on the first anticoagulant clinic appointment, and when necessary throughout the course of their treatment (NPSA Alert 18) |
Drug status key
Formulary drugs are allocated a traffic light status. This provides guidance on where clinical and prescribing responsibilities lie in regard to the initiation and maintenance of prescribing.
Grey
Positive NICE TA and/or awaiting local clarification on place in therapy. Please contact your medicines optimisation team for more information.
Red
Initiation and maintenance of prescribing by specialists only.
Amber
Initiation and maintenance of prescribing by specialists and transfer to primary care prescribing when appropriate, or in primary care following a specialists recommendation. Prior to initiation some medicines may require committee agreement or a framework to support safe transfer and maintenance.
Green
Initiation and maintenance of prescribing by specialists, GPs and other qualified clinicians.
Blue
Under review at University Hospitals Birmingham NHS Foundation Trust.