University Hospitals Birmingham NHS Foundation Trust

Chapters

StatusDrug nameNICE TAsComments
Status: GreenAlogliptin (Vipidia®)

1st line choice

Status: GreenCanagliflozin
Status: AmberContinous glucose monitoring system (Dexcom ONE®)
Status: GreenDapagliflozin

For treating Type 2 diabetes in line with NICE 

Status: GreenDapagliflozin (Forxiga®)
Status: AmberDapagliflozin
Status: RedDapagliflozin

Specialist centres only for treating Type 1 diabetes

Status: GreenDulaglutide (Trulicity®)

Not for monotherapy. Not in combination with insulin.

Status: GreenEmpagliflozin
Status: AmberEmpagliflozin (Jardiance®)
Status: AmberEmpaglifozin
Status: GreenEmpaglifozin
Status: GreenErtugliflozin (Steglatro®)
Status: GreenExenatide prolonged release injection (Bydureon®)
Status: AmberFlash glucose monitoring system  (FreeStyle Libre 2®, FreeStyle Libre®)
Status: AmberGlibenclamide tablets

For patients who do not want to move to insulin but not responding to metformin

Status: GreenGlicazide M/R tablets

2nd line option

Status: GreenGlicazide tablets
Status: GreenGlimepiride tablets
Status: GreenGlucagon hypokit
Status: GreenGlucose 40% oral gel
Status: GreenInsulin actrapid® injection (10ml)

Prescribe by brand name

Status: AmberInsulin aspart (Fiasp®)

Prescribe by brand name. For specialist use in pregnancy.

Status: GreenInsulin aspart (Novorapid®) injection

Prescribe by brand name

Status: AmberInsulin degludec 100 units/ml (Tresiba®)

Amber for type 1 diabetes- specialist initiation. RICaD. Red for Type 2 diabetes.                                        

Status: RedInsulin degludec 100 units/ml (Tresiba®)

Amber for type 1 diabetes- specialist initiation. RICaD. Red for Type 2 diabetes.     

Status: GreenInsulin detemir (Levemir®)

Prescribe by brand name

Status: AmberInsulin glargene 300 units/ml (Toujeo®)

Specialist initiation. For patients who require more than 80 units of insulin glargine per day and who are troubled by nocturnal hypos. Transfer to Primary Care should not happen until specialists can demonstrate reduction in nocturnal hypos (e.g. after 3–4 months). RICaD.

Status: GreenInsulin glargine (lantus®)

Extremely high relative cost. Prescribe by brand name.

Status: GreenInsulin glargine 100 units/ml (Abasalgar®)

Prescribe by brand name. First line for new patients initiated on insulin glargine 100 units/ml.

Status: GreenInsulin glulisine (Apidra)

Prescribe by brand name

Status: GreenInsulin humalog® mix 25

Prescribe by brand name

Status: GreenInsulin humalog® mix 50

Prescribe by brand name

Status: GreenInsulin humulin I® injection

Prescribe by brand name

Status: GreenInsulin humulin S® injection

Prescribe by brand name

Status: GreenInsulin humulin® M3 injection

Prescribe by brand name

Status: GreenInsulin hypurin® bovine isophane injection

For existing patients only

Status: GreenInsulin hypurin® bovine lente injection

For existing patients only

Status: GreenInsulin hypurin® bovine neutral injection

For existing patients only

Status: GreenInsulin hypurin® bovine protamine zinc injection

For existing patients only

Status: GreenInsulin hypurin® porcine 30/70 injection

For existing patients only

Status: GreenInsulin hypurin® porcine isophane injection

For existing patients only

Status: GreenInsulin hypurin® porcine neutral inj (10ml)

For existing patients only

Status: GreenInsulin insulatard® injection

Prescribe by brand name

Status: GreenInsulin insuman® basal

Prescribe by brand name

Status: GreenInsulin insuman® comb 15 injection

Prescribe by brand name

Status: GreenInsulin insuman® comb 25 injection

Prescribe by brand name

Status: GreenInsulin insuman® comb 50 injection

Prescribe by brand name

Status: GreenInsulin insuman® rapid injection

Prescribe by brand name

Status: GreenInsulin lispro 100 units/ml (Humalog®) injection

Prescribe by brand name

Status: GreenInsulin novomix® 30 injection

Prescribe by brand name

Status: RedIV fluids

Hospital only

Status: GreenLinagliptin tablets
Status: RedLiraglutide (Saxenda®) (GLP1s should all be prescribed by brand name)

The use of Liraglutide for this indication is restricted to prescribing in secondary care by a specialist multidisciplinary Tier 3 weight management service with a commercial agreement in place.

Prescribe by brand (Saxenda®) to avoid patients inadvertently receiving a different product licensed for type 2 diabetes.

Status: GreenLiraglutide (Victoza®) injection (GLP1s should all be prescribed by brand name)

THIS IS FOR DIABETES ONLY. Prescribe by brand (Victoza®) to avoid patients inadvertently receiving a different product licensed for obesity.

1.8 mg is non-formulary.

Status: GreenLixisenatide (Lyxumia®)

1st line choice GLP1 for co-prescribing with insulin. RICaD.

Status: GreenMetformin liquid
Status: GreenMetformin M/R tablets

2nd line - only for patients intolerant of slowly titrated standard release metformin. Sukkarto SR 500mg and 1000mg.

Status: GreenMetformin tablets
Status: GreenPioglitazone tablets
Status: GreenRepaglinide tablets
Status: RedSemaglutide (Wegovy®)

The use of semaglutide for this indication is restricted to prescribing in secondary care by a specialist multidisciplinary Tier 3 weight management service with a commercial agreement in place.

Prescribe by brand (Wegovy®) to avoid patients inadvertently receiving a different product licensed for type 2 diabetes.

The Wegovy® brand of semaglutide is not commercially available yet.

Status: GreenSemaglutide solution for injection (Ozempic®)
Status: GreenSemaglutide tablets (Rybelsus®) (GLP1s should all be prescribed by brand name)
Status: GreenSitagliptin tablets
Status: RedSoluble insulin

Hospital only

Status: GreenTirzepatide (Mounjaro®)

Drug status key

Formulary drugs are allocated a traffic light status. This provides guidance on where clinical and prescribing responsibilities lie in regard to the initiation and maintenance of prescribing.

Grey

Grey

Positive NICE TA and/or awaiting local clarification on place in therapy. Please contact your medicines optimisation team for more information.

Red

Red

Initiation and maintenance of prescribing by specialists only.

Amber

Amber

Initiation and maintenance of prescribing by specialists and transfer to primary care prescribing when appropriate, or in primary care following a specialists recommendation. Prior to initiation some medicines may require committee agreement or a framework to support safe transfer and maintenance.

Green

Green

Initiation and maintenance of prescribing by specialists, GPs and other qualified clinicians.

Blue

Blue

Under review at University Hospitals Birmingham NHS Foundation Trust.

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