Medicines Formulary

Reports

Drug name	NICE TAs	Comments
Doxorubicin liposomal infusion	TA91 - Paclitaxel, pegylated liposomal doxorubicin hydrochloride and topotecan for second-line or subsequent treatment of advanced ovarian cancer TA389 - Topotecan, pegylated liposomal doxorubicin hydrochloride, paclitaxel, trabectedin and gemcitabine for treating recurrent ovarian cancer	National CDF list
Duaklir Genuair		Aclidinium bromide + formoterol fumarate (Fixed Dose Combination). To be used in in-line with COPD Guidance.
Dulaglutide (Trulicity®)		Not for monotherapy. Not in combination with insulin.
Duloxetine capsules (Cymbalta)		Specialist initiation only
Dutasteride capsules		RICaD
Edoxaban	TA355 - Edoxaban for preventing stroke and systemic embolism in people with non-valvular atrial fibrillation TA354 - Edoxaban for treating and for preventing deep vein thrombosis and pulmonary embolism	First choice following a diagnosis of AF - use in line with NICE Anticoagulant Initiation Flowchart for Anticoagulation in Atrial Fibrillation
Edoxaban	TA355 - Edoxaban for preventing stroke and systemic embolism in people with non-valvular atrial fibrillation TA354 - Edoxaban for treating and for preventing deep vein thrombosis and pulmonary embolism	Specialist initiation - For the treatment and secondary prevention of DVT and/or PE - use in line with NICE and supported by RICaD Anticoagulant Initiation Flowchart for Anticoagulation in Atrial Fibrillation
Eliglustat (Cerdelga®)		NHSE commissioned
Elosulfase lfa (Vimizim®)		NHSE commissioned
Eluxadoline (Truberzi®)	TA471 - Eluxadoline for treating irritable bowel syndrome with diarrhoea	To be used in line with NICE TA 471. Specialist initiation, and transfer prescribing to GP using RICaD (in development).

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Drug status key

Formulary drugs are allocated a traffic light status. This provides guidance on where clinical and prescribing responsibilities lie in regard to the initiation and maintenance of prescribing.

Grey

Positive NICE TA and/or awaiting local clarification on place in therapy. Please contact your medicines optimisation team for more information.

Red

Initiation and maintenance of prescribing by specialists only.

Amber

Initiation and maintenance of prescribing by specialists and transfer to primary care prescribing when appropriate, or in primary care following a specialists recommendation. Prior to initiation some medicines may require committee agreement or a framework to support safe transfer and maintenance.

Green

Initiation and maintenance of prescribing by specialists, GPs and other qualified clinicians.

Blue

Under review at University Hospitals Birmingham NHS Foundation Trust.